EP-1187: Reirradiation using 3DCRT in recurrent brain gliomas: Survival and prognostic factors
نویسندگان
چکیده
منابع مشابه
Phase II trial of temozolomide and reirradiation using conformal 3D-radiotherapy in recurrent brain gliomas.
PURPOSE This phase II trial was designed to assess the response rate, survival benefits and toxicity profile of temozolomide, and brain reirradiation using conformal radiotherapy (RT) for treatment of recurrent high grade glioma. DESIGN Open-label phase II trial. PATIENTS Twenty-nine patients had been enrolled in the study between February 2006 and June 2009. Patients had to show unequivoca...
متن کاملExternal validation of a prognostic model estimating the survival of patients with recurrent high-grade gliomas after reirradiation.
PURPOSE We aimed to validate a controversial prognostic model for the survival of relapsed malignant glioma patients after reirradiation with an independent, multicentric patient cohort. METHODS AND MATERIALS A total of 165 malignant glioma patients underwent reirradiation at 4 different institutions between 1994 and 2012. Twenty-two patients had a good (score 1), 44 had a moderate (score 2),...
متن کاملSURVIVAL IN PATIENTS WITH MALIGNANT GLIOMAS OF THE BRAIN
The present retrospective study was designed to analyze factors with prognostic values a) within, and b) significantly associated with, short-term (12months or less) and long-term (more than 24 months) survival times, i n 72 consecutive patients treated for malignant gliomas. Among 41 (57%) short-term surviving patients, the absence of both aphasia and motor deficit (as initial presenting ...
متن کاملA thought-provoking retrospective study on survival and toxicity after reirradiation for recurrent high-grade gliomas.
TO THE EDITOR: Fogh et al recently published a large singleinstitution study on hypofractionated stereotactic reirradiation for recurrent high-grade gliomas in which 147 patients were included, the vast majority (71%) with glioblastoma. The median initial radiotherapy dose was 60 Gy, and the median reirradiation dose was 35 Gy in 3.5-Gy fractions. Median time from diagnosis to reirradiation was...
متن کاملRe-Irradiation for Recurrent Gliomas: Treatment Outcomes and Prognostic Factors
PURPOSE The aim of this study was to evaluate the efficacy of re-irradiation in patients with recurrent gliomas and to identify subgroups for whom re-irradiation for recurrent gliomas is most beneficial. MATERIALS AND METHODS We retrospectively reviewed 36 patients with recurrent or progressive gliomas who received re-irradiation between January 1996 and December 2011. Re-irradiation was offe...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2018
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(18)31497-x